Detailed Description
SS-31, also known as elamipretide, is a laboratory-synthesized tetrapeptide designed to selectively associate with mitochondrial membranes. In research environments, SS-31 is utilized as a molecular probe to examine mitochondrial structure, membrane dynamics, and signaling processes associated with cellular bioenergetics.
Due to its targeted affinity for mitochondrial components, SS-31 enables focused investigation of mitochondrial function, oxidative signaling pathways, and intracellular energy regulation within controlled experimental systems. All research involving SS-31 is conducted strictly at the biochemical and mechanistic level and does not imply physiological, diagnostic, or clinical outcomes.
Biochemical Properties
Properties
Synthetic mitochondria-targeting tetrapeptide
Bioenergetic signaling research compound
Structure
Linear tetrapeptide
Class
Mitochondrial signaling peptide research compound
Behavior
Associates with mitochondrial membranes and related signaling components in experimental systems
Solubility or Stability
Soluble in aqueous laboratory media following appropriate preparation
Stable in lyophilized form under controlled storage conditions
Identifiers
Chemical Name: SS-31 (Elamipretide)
CAS Number: 736992-21-5
Molecular Formula: C32H49N9O5
Molecular Weight: 639.8 g/mol
Structural & Molecular Data
Amino Acid Sequence: D-Arg-2′,6′-dimethylTyr-Lys-Phe-NH2
Molecular Formula: C32H49N9O5
Molecular Weight: 639.8 g/mol
PubChem CID: 11764719
Structural Notes
SS-31’s short peptide sequence and aromatic residues contribute to selective mitochondrial membrane interaction, supporting targeted bioenergetic signaling analysis in experimental models.
Scientific Description
Overview
SS-31 is investigated as a peptide-based research tool for examining mitochondrial signaling, membrane dynamics, and intracellular energy regulation.
Biochemical Characteristics
In preclinical research systems, SS-31 has been studied for its interaction with mitochondrial phospholipid environments, influence on electron transport–associated signaling, and modulation of oxidative stress–related pathways at the molecular level.
Experimental Research Scope
Mitochondrial membrane interaction studies
Cellular bioenergetics signaling analysis
Oxidative pathway and redox signaling research
Intracellular energy regulation investigations
Molecular and Signaling Context
Mitochondria serve as central hubs for cellular energy production and signaling. SS-31 enables controlled investigation of mitochondrial-specific pathways and membrane-associated signaling mechanisms within laboratory research environments.
Summary of Preclinical Investigation
SS-31 has been evaluated in cellular and animal research models to characterize mitochondrial targeting behavior, signaling specificity, and pathway integration. These investigations emphasize mechanistic understanding rather than physiological or clinical endpoints.
Form & Analytical Testing
Form: Lyophilized solid
Appearance: White to off-white lyophilized powder
Quantity per vial: 10 mg
Analytical methods: HPLC, MS
Identity and purity verified prior to release